abstract：:The association between childhood adversity (CA) and psychosis has been extensively investigated in recent years. An increasing body of research has also focused on the mediating or moderating role of biological and psychological mechanisms, as well as other risk factors that might account for the link between CA and ...

journal_title：Psychological medicine

authors： Sideli L,Murray RM,Schimmenti A,Corso M,La Barbera D,Trotta A,Fisher HL

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Temperament and personality traits, including negative emotionality/neuroticism, may represent risk factors for eating disorders. Further, risk factors may differ by sex. We examined longitudinal temperament/personality pathways of risk for purging and binge eating in youth stratified by sex using data from ...

journal_title：Psychological medicine

authors： Brown M,Hochman A,Micali N

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Maternal depression during pregnancy increases the risk for adverse developmental outcomes in children. However, the underpinning biological mechanisms remain unknown. We tested whether depression was associated with levels of and change in the inflammatory state during pregnancy, if early pregnancy overweig...

journal_title：Psychological medicine

authors： Lahti-Pulkkinen M,Girchenko P,Robinson R,Lehto SM,Toffol E,Heinonen K,Reynolds RM,Kajantie E,Laivuori H,Villa PM,Hämäläinen E,Lahti J,Räikkönen K

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Virtual reality (VR) may enhance the effectiveness of psychological interventions for acute pain. We conducted a meta-analysis to assess the efficacy and safety of VR-based interventions for pain associated with medical procedures. METHODS:We searched PubMed, EMBASE, the Cochrane Library, and PsycINFO until...

journal_title：Psychological medicine

authors： Georgescu R,Fodor LA,Dobrean A,Cristea IA

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) is accompanied by alterations in grey matter volume. However, the biological processes associated with regional structural perturbations remain elusive. METHODS:We applied integrative omics analysis to investigate specialized transcriptome signatures and translational determi...

journal_title：Psychological medicine

authors： Sha Z,Banihashemi L

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:A few previous studies suggest that a large number of individuals do not present at hospital following a suicide attempt, complicating recurrence prevention and prevalence estimation. METHODS:Data were extracted from a regular phone survey in representative samples of the French population aged 18-75 years ...

journal_title：Psychological medicine

authors： Jollant F,Hawton K,Vaiva G,Chan-Chee C,du Roscoat E,Leon C

更新日期：2020-07-03 00:00:00

abstract：BACKGROUND:Evidence from high-income countries suggests that childhood trauma is associated with schizophrenia. Studies of childhood trauma and schizophrenia in low and middle income (LMIC) countries are limited. This study examined the prevalence of childhood traumatic experiences among cases and controls and the rela...

journal_title：Psychological medicine

authors： Mall S,Platt JM,Temmingh H,Musenge E,Campbell M,Susser E,Stein DJ

更新日期：2020-07-01 00:00:00

abstract：:Taxometric procedures have been used extensively to investigate whether individual differences in personality and psychopathology are latently dimensional or categorical ('taxonic'). We report the first meta-analysis of taxometric research, examining 317 findings drawn from 183 articles that employed an index of the c...

journal_title：Psychological medicine

authors： Haslam N,McGrath MJ,Viechtbauer W,Kuppens P

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) is associated with reduced life expectancy in patients with affective disorders, however, whether MetS also plays a role before the onset of affective disorder is unknown. We aimed to investigate whether MetS, inflammatory markers or oxidative stress act as risk factors for affectiv...

journal_title：Psychological medicine

authors： Ottesen NM,Meluken I,Frikke-Schmidt R,Plomgaard P,Scheike T,Fernandes BS,Berk M,Poulsen HE,Kessing LV,Miskowiak K,Vinberg M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Two types of mentalization-based treatment (MBT), day hospital MBT (MBT-DH) and intensive outpatient MBT (MBT-IOP), have been shown to be effective in treating patients with borderline personality disorder (BPD). This study evaluated trajectories of change in a multi-site trial of MBT-DH and MBT-IOP at 36 mo...

journal_title：Psychological medicine

authors： Smits ML,Feenstra DJ,Bales DL,Blankers M,Dekker JJM,Lucas Z,Kamphuis JH,Busschbach JJV,Verheul R,Luyten P

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:The development of childhood anxiety disorders (CADs) is likely to depend on pathways that can be programmed by early-life risk factors. We test the hypothesis that early-life maternal factors can predict this programming effect on CAD. METHODS:Data were obtained from 198 women and children from the Mercy P...

journal_title：Psychological medicine

authors： Galbally M,Watson SJ,van Rossum EFC,Chen W,de Kloet ER,Lewis AJ

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Nitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS activity of patients with a MDE to that of healthy controls (HC); (2)...

journal_title：Psychological medicine

authors： Loeb E,El Asmar K,Trabado S,Gressier F,Colle R,Rigal A,Martin S,Verstuyft C,Fève B,Chanson P,Becquemont L,Corruble E

更新日期：2020-06-11 00:00:00

abstract：BACKGROUND:Seeking compensation has been shown to have an adverse effect on the psychological health and recovery of injured patients, however, this effect requires clarification. METHODS:A total of 2019 adults sustaining a traffic injury were recruited. Of these, 709 (35.1%) lodged a compensation claim. Interviews oc...

journal_title：Psychological medicine

authors： Pozzato I,Kifley A,Craig A,Gopinath B,Tran Y,Jagnoor J,Cameron ID

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:Social media platforms have long been recognised as major disseminators of health misinformation. Many previous studies have found a negative association between health-protective behaviours and belief in the specific form of misinformation popularly known as 'conspiracy theory'. Concerns have arisen regardi...

journal_title：Psychological medicine

authors： Allington D,Duffy B,Wessely S,Dhavan N,Rubin J

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:Parental characteristics and practices predict borderline personality disorder (BPD) symptoms in children. However, it is difficult to disentangle whether these effects are genetically or environmentally mediated. The present study examines the contributions of genetic and environmental influences by compari...

journal_title：Psychological medicine

authors： Fatimah H,Wiernik BM,Gorey C,McGue M,Iacono WG,Bornovalova MA

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Men sexually interested in children of a specific combination of maturity and sex tend to show some lesser interest in other categories of persons. Patterns of men's sexual interest across erotic targets' categories of maturity and sex have both clinical and basic scientific implications. METHOD:We examined...

journal_title：Psychological medicine

authors： Bailey JM,Blanchard R,Hsu KJ,Revelle W

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Item 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The PHQ-8, which omits Item 9, is thus increasingly used in research. We ...

journal_title：Psychological medicine

authors： Wu Y,Levis B,Riehm KE,Saadat N,Levis AW,Azar M,Rice DB,Boruff J,Cuijpers P,Gilbody S,Ioannidis JPA,Kloda LA,McMillan D,Patten SB,Shrier I,Ziegelstein RC,Akena DH,Arroll B,Ayalon L,Baradaran HR,Baron M,Bombardier

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:There is uncertainty about the incidence of breakthrough psychosis in treatment adherent patients, and the role that factors, such as cumulative antipsychotic exposure, play in this phenomenon. METHODS:In a nationwide cohort of individuals treated for schizophrenia-spectrum disorders in Finland between 1 Ja...

journal_title：Psychological medicine

authors： Rubio JM,Taipale H,Correll CU,Tanskanen A,Kane JM,Tiihonen J

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) is highly heterogeneous and can be classified as treatment-resistant depression (TRD) or antidepressant-responsive depression (non-TRD) based on patients' responses to antidepressant treatment. Methods for distinguishing between TRD and non-TRD are critical clinical concerns. ...

journal_title：Psychological medicine

authors： Jeng JS,Li CT,Lin HC,Tsai SJ,Bai YM,Su TP,Chang YW,Cheng CM

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Euthanasia and assisted suicide (EAS) based on a psychiatric disorder (psychiatric EAS) continue to pose ethical and policy challenges, even in countries where the practice has been allowed for years. We conducted a systematic review of reasons, a specific type of review for bioethical questions designed to ...

journal_title：Psychological medicine

authors： Nicolini ME,Kim SYH,Churchill ME,Gastmans C

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Early life maltreatment (ELM), borderline personality disorder (BPD), and major depressive disorder (MDD) have been associated with empathy deficits in different domains. Lack of maternal empathy has also been related to child behavioral problems. As ELM, BPD, and MDD often co-occur, we aimed to identify dis...

journal_title：Psychological medicine

authors： Dittrich K,Bermpohl F,Kluczniok D,Hindi Attar C,Jaite C,Fuchs A,Neukel C,Herpertz SC,Brunner R,Winter SM,Lehmkuhl U,Roepke S,Kaess M,Heim C,Boedeker K

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:To estimate the lifetime prevalence and potential determinants of psychotic experience(s) (PEs) in the general population of Qatar - a small non-war afflicted, conservative, high-income, middle-eastern country with recent rapid urbanization including an influx of migrants. METHODS:A probability-based sample...

journal_title：Psychological medicine

authors： Khaled SM,Wilkins SS,Woodruff P

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Pharmacological treatments targeting the neuroendocrine stress response may hold special promise in secondary prevention of posttraumatic stress disorder (PTSD). However, findings from clinical trials have been inconsistent and the efficacy of specific drugs, their temporal window of efficacy, effective dose...

journal_title：Psychological medicine

authors： Kamboj SK,Gong AT,Sim Z,Rashid AA,Baba A,Iskandar G,Das RK,Curran HV

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Schizophrenia (SZ) is a complex disorder characterized by a range of behavioral and cognitive symptoms as well as structural and functional alterations in multiple cortical and subcortical structures. SZ is associated with reduced functional network connectivity involving core regions such as the anterior ci...

journal_title：Psychological medicine

authors： Csukly G,Szabó Á,Polgár P,Farkas K,Gyebnár G,Kozák LR,Stefanics G

更新日期：2020-04-24 00:00:00

abstract：BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...

journal_title：Psychological medicine

authors： Laskemoen JF,Aas M,Vaskinn A,Berg AO,Lunding SH,Barrett EA,Melle I,Simonsen C

更新日期：2020-04-23 00:00:00

abstract：BACKGROUND:Although hallucinations have been studied in terms of prevalence and its associations with psychopathology and functional impairment, very little is known about sensory modalities other than auditory (i.e. haptic, visual and olfactory), as well the incidence of hallucinations, factors predicting incidence an...

journal_title：Psychological medicine

authors： Moriyama TS,Drukker M,Guloksuz S,Ten Have M,de Graaf R,van Dorsselaer S,Gunther N,Bak M,van Os J

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND:To provide an overview of epidemiological studies of dementia among migrant groups in Europe and to estimate their pooled odds ratio (OR) v. the reference population. METHODS:Search for articles reporting on incidence or prevalence of dementia among ethnic minorities and migrants in Europe, published before...

journal_title：Psychological medicine

authors： Selten JP,Termorshuizen F,van Sonsbeek M,Bogers J,Schmand B

更新日期：2020-04-08 00:00:00

abstract：BACKGROUNDS:Cigarette smoking is strongly associated with major depressive disorder (MDD). However, any genetic etiology of such comorbidity and causal relations is poorly understood, especially at the genome-wide level. METHODS:In the present in silico research, we analyzed summary data from the genome-wide associati...

journal_title：Psychological medicine

authors： Yao Y,Xu Y,Cai Z,Liu Q,Ma Y,Li AN,Payne TJ,Li MD

更新日期：2020-04-06 00:00:00

abstract：:Animal experimental studies suggest that 5-HT4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 5-HT4 receptors are post-synaptic receptors that are located in striatal and limbic areas known to be involved in cognition and mood. Consistent with this, 5-HT4 ...

journal_title：Psychological medicine

authors： Murphy SE,de Cates AN,Gillespie AL,Godlewska BR,Scaife JC,Wright LC,Cowen PJ,Harmer CJ

更新日期：2020-04-03 00:00:00

abstract：BACKGROUND:The output of many healthy physiological systems displays fractal fluctuations with self-similar temporal structures. Altered fractal patterns are associated with pathological conditions. There is evidence that patients with bipolar disorder have altered daily behaviors. METHODS:To test whether fractal patt...

journal_title：Psychological medicine

authors： Knapen SE,Li P,Riemersma-van der Lek RF,Verkooijen S,Boks MPM,Schoevers RA,Scheer FAJL,Hu K

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Previous studies have provided initial evidence that people at risk for psychosis (PR) suffer from stigma and discrimination related to their condition. However, no study has systematically reviewed stigma and discrimination associated with being at PR and the potential underlying mechanisms. METHODS:This w...

journal_title：Psychological medicine

authors： Colizzi M,Ruggeri M,Lasalvia A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Trans and gender diverse (TGD) young people worldwide experience high rates of poor mental health; however, these rates were unknown in Australia. In addition, how negative life events affect the mental health of TGD young people has been largely unexplored. METHODS:This paper reports on novel mental health...

journal_title：Psychological medicine

authors： Strauss P,Cook A,Winter S,Watson V,Wright Toussaint D,Lin A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Low IQ is a risk factor for psychosis, but the effect of high IQ is more controversial. The aim was to explore the association of childhood school success with prodromal symptoms in adolescence and psychoses in adulthood. METHODS:In the general population-based Northern Finland Birth Cohort 1986 (n = 8 229)...

journal_title：Psychological medicine

authors： Lassila M,Nordström T,Hurtig T,Mäki P,Jääskeläinen E,Oinas E,Miettunen J

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The Psychiatric Genomics Consortium (PGC) has made major advances in the molecular etiology of MDD, confirming that MDD is highly polygenic. Pathway enrichment results from PGC meta-analyses can also be used to help inform molecular drug targets. Prior to any knowledge of molecular biomarkers for MDD, drugs ...

journal_title：Psychological medicine

authors： Docherty AR,Moscati A,Bigdeli TB,Edwards AC,Peterson RE,Adkins DE,Anderson JS,Flint J,Kendler KS,Bacanu SA

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Bipolar disorder I (BD-I) is defined by episodes of mania, depression and euthymic states. These episodes are among other symptoms characterized by altered reward processing and negative symptoms (NS), in particular apathy. However, the neural correlates of these deficits are not well understood. METHODS:We...

journal_title：Psychological medicine

authors： Kirschner M,Cathomas F,Manoliu A,Habermeyer B,Simon JJ,Seifritz E,Tobler PN,Kaiser S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Children of parents with mood and psychotic disorders are at elevated risk for a range of behavioral and emotional problems. However, as the usual reporter of psychopathology in children is the parent, reports of early problems in children of parents with mood and psychotic disorders may be biased by the par...

journal_title：Psychological medicine

authors： Sandstrom A,MacKenzie L,Pizzo A,Fine A,Rempel S,Howard C,Stephens M,Patterson VC,Drobinin V,Van Gestel H,Howes Vallis E,Zwicker A,Propper L,Abidi S,Bagnell A,Lovas D,Cumby J,Alda M,Uher R,Pavlova B

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Resting pulse is robustly and inversely associated with the risk for externalizing disorders and may be positively associated with internalizing disorders. We know little about the causal nature of these associations. METHODS:We examined resting pulse at conscription examination in 369 301 males born 1960-8...

journal_title：Psychological medicine

authors： Kendler KS,Lönn SL,Sundquist J,Sundquist K

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Hierarchical structural models of psychopathology rarely extend to obsessive-compulsive spectrum disorders. The current study sought to examine the higher-order structure of the obsessive-compulsive and related disorders (OCRDs) in DSM-5: obsessive-compulsive disorder (OCD), hoarding disorder (HD), body dysm...

journal_title：Psychological medicine

authors： Snorrason I,Beard C,Peckham AD,Björgvinsson T

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Psychiatric disorders and related intermediate phenotypes are highly heritable and have a complex, overlapping polygenic architecture. A large-scale genome-wide association study (GWAS) of anxiety disorders identified genetic variants that are significant on a genome-wide. The current study investigated the ...

journal_title：Psychological medicine

authors： Ohi K,Otowa T,Shimada M,Sasaki T,Tanii H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The USA is currently enduring an opioid crisis. Identifying cost-effective, easy-to-implement behavioral measures that predict treatment outcomes in opioid misusers is a crucial scientific, therapeutic, and epidemiological goal. METHODS:The current study used a mixed cross-sectional and longitudinal design ...

journal_title：Psychological medicine

authors： Moeller SJ,Hanley AW,Garland EL

更新日期：2020-03-01 00:00:00